It's a Fran Drescher-themed AMV with watermark-embossed, DVD-ripped footage that is just above Sega CD-quality, and the whole thing is set to the opening theme to Suite PreCure. You can watch this video if you dare, but I guarantee you will not be the same person you were before you watched it.
And I thought I was the only anime-fan with arcane knowledge of late 80s/early 90s sitcoms. Turns out I'm still the only one who's not crazy, though.
If you'd like a palate cleanser, here's a video that shows you what that song is supposed to look like.